ITGB1 monoclonal antibody, clone DF7
产品名称: ITGB1 monoclonal antibody, clone DF7
英文名称: ITGB1 monoclonal antibody, clone DF7
产品编号: MAB5274
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
                            亚诺法生技股份有限公司(Abnova)
                            
                                
                            
                        
                    - 联系人 :
 - 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
 - 邮编 : 11493
 - 所在区域 : 台湾
 - 电话 : +886-920**1152 点击查看
 - 传真 : 点击查看
 - 邮箱 : sales@abnova.com.tw
 
- Specification
 
- Product Description:
 - Mouse monoclonal antibody raised against native ITGB1.
 
- Immunogen:
 - Native purified human ITGB1.
 
- Host:
 - Mouse
 
- Reactivity:
 - Human
 
- Specificity:
 - This antibody reacts with the b1 subunit of the integrin protein family. The monoclonal antibody reacts with an extracellular epitope of the b1 integrin molecule. b1 -Integrins mediate cell-extracellular matrix interactions and share a common b-subunit. Monoclonal antibodies against this b1 -Integrin subunit are applicable in paraffin-embedded and frozen sections, immunoblotting and immunoprecipitation. Numerous studies have shown that b1 -Integrins have a distinct and wide cellular distribution and that there are alterations in malignant cells in their b1-integrin expression. Monoclonal antibody to b1 integrin is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.
 
- Form:
 - Liquid
 
- Isotype:
 - IgG1
 
- Storage Buffer:
 - In PBS (1% BSA, 0.1% sodium azide)
 
- Storage Instruction:
 - Store at 4°C.
 
- Recommend Usage:
 - Western Blot (1:1000)
The optimal working dilution should be determined by the end user. 
- Note:
 - This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
 
- Application Image
 
- Western Blot
 
- ELISA
 
- Entrez GeneID:
 - 3688
 
- Gene Name:
 - ITGB1
 
- Gene Alias:
 - CD29,FNRB,GPIIA,MDF2,MSK12,VLA-BETA,VLAB
 
- Gene Description:
 - integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
 
- Omim ID:
 - 135630
 
- Gene Ontology:
 - Hyperlink
 
- Gene Summary:
 - Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq
 
- Other Designations:
 - OTTHUMP00000019420,OTTHUMP00000046253,OTTHUMP00000063731,OTTHUMP00000063732,OTTHUMP00000063733,fibronectin receptor beta subunit,integrin VLA-4 beta subunit,integrin beta 1
 
- Gene Pathway
 
- Arrhythmogenic right ventricular cardiomyopathy (ARVC)
 - Axon guidance
 - Cell adhesion molecules (CAMs)
 - ECM-receptor interaction
 - Focal adhesion
 - Hypertrophic cardiomyopathy (HCM)
 - Leukocyte transendothelial migration
 - Pathogenic Escherichia coli infection - EHEC
 - Pathways in cancer
 - Regulation of actin cytoskeleton
 - Small cell lung cancer
 
