ATF6 polyclonal antibody
产品名称： ATF6 polyclonal antibody
英文名称： ATF6 polyclonal antibody
产品编号： PAB14606
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of ATF6.
- Immunogen:
- A synthetic peptide corresponding to amino acids 491-509 of human ATF6.
- Sequence:
- EVERTKSRRMTNNQQKTRI
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Storage Buffer:
- In serum (50% glycerol, 0.025% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:100-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs.
Ye J, Rawson RB, Komuro R, Chen X, Dave UP, Prywes R, Brown MS, Goldstein JL.Mol Cell. 2000 Dec;6(6):1355-64.
- 2.
- Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress.
Haze K, Yoshida H, Yanagi H, Yura T, Mori K.Mol Biol Cell. 1999 Nov;10(11):3787-99.
- 3.
- Interaction of ATF6 and serum response factor.
Zhu C, Johansen FE, Prywes R.Mol Cell Biol. 1997 Sep;17(9):4957-66.
- Application Image
- ELISA
- Entrez GeneID:
- 22926
- Protein Accession#:
- NP_031374
- Gene Name:
- ATF6
- Gene Alias:
- ATF6A
- Gene Description:
- activating transcription factor 6
- Omim ID:
- 605537
- Gene Ontology:
- Hyperlink
- Gene Summary:
- ATF6 is an endoplasmic reticulum (ER) stress-regulated transmembrane transcription factor that activates the transcription of ER molecules.[supplied by OMIM
- Other Designations:
- OTTHUMP00000025585,activating transcription factor 6 alpha
- Gene Pathway